p38 MAPK Inhibitors

p38 MAPK

p38α

p38β

MAPK13

p38δ

p38γ

p38 MAPK p53 Inhibitors, Inhibitors, Agonists & Activators

Product Name	p38 MAPK	p38α	p38β	MAPK13	p38δ	p38γ	Purity
Adezmapimod	p38, IC₅₀: 50 nM		p38β2, IC₅₀: 500 nM				99.96%
SB 202190		p38α, IC₅₀: 50 nM	p38β2, IC₅₀: 100 nM				99.89%
Doramapimod	p38 MAP kinase, Kd: 0.1 nM	p38α, IC₅₀: 38 nM	p38β, IC₅₀: 65 nM		p38δ, IC₅₀: 520 nM	p38γ, IC₅₀: 200 nM	99.98%
Adezmapimod hydrochloride	p38, IC₅₀: 50 nM		p38β2, IC₅₀: 500 nM				99.71%
Muramyl dipeptide	p38 MAPK						≥98.0%
Diprovocim	p38 MAPK						98.35%
Ralimetinib dimesylate		p38α MAPK, IC₅₀: 5.3 nM	p38β MAPK, IC₅₀: 3.2 nM				99.91%
Naporafenib		p38α, IC₅₀: 2.1 μM					99.72%
Neflamapimod		p38α, IC₅₀: 10 nM	p38β, IC₅₀: 220 nM				99.32%
Exarafenib	p38 MAPK						99.68%
Skatole	p38						99.97%
Talmapimod		p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM				98.97%
Semapimod tetrahydrochloride	p38 MAPK						98.43%
Tpl2 Kinase Inhibitor 1	p38, IC₅₀: 180 μM						99.22%
Esculin	p38 MAPK						99.78%
Paris saponin VII	p38						99.96%
p38 MAPK-IN-1	p38 MAPK, IC₅₀: 68 nM						99.45%
TAK-715		p38α, IC₅₀: 7.1 nM	p38β, IC₅₀: 200 nM		p38δ, IC₅₀: >10 μM	p38γ, IC₅₀: >10 μM	99.73%
Broussonin E	p38 MAPK						98.18%
MAPK13-IN-1				MAPK13 (p38δ), IC₅₀: 620 nM			98.93%
AMG-548 dihydrochloride		p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM	99.91%
Peimine	p38						99.40%
BMS-582949 hydrochloride		p38α MAPK, IC₅₀: 13 nM					98.90%
SB 202190 hydrochloride		p38α, IC₅₀: 50 nM	p38β2, IC₅₀: 100 nM				99.84%
UM-164		p38α	p38β				99.15%
MKK7-COV-9	p38 MAP kinase
Gossypetin	p38 MAP kinase						99.82%
MW-150		p38α, Ki: 101 nM					99.89%
Dihydrocaffeic acid	p38 MAPK						99.38%
EW-7195		p38α, IC₅₀: 1.5 μM					99.20%
Cornuside	p38 MAP kinase						99.95%
Pamapimod		p38α, IC₅₀: 14 nM p38α, Ki: 1.3 nM	p38β, IC₅₀: 480 p38β, Ki: 120 nM				99.92%
Isoliquiritin apioside	p38 MAPK						99.87%
TA-01	p38 MAP kinase, IC₅₀: 6.7 nM						99.86%
NF-κB/MAPK-IN-1	p38						98.42%
Rotundic acid	p38 MAPK						99.41%
Ferulic acid methyl ester	p38						99.95%
Emprumapimod		p38α					99.12%
SM-7368	p38 MAP kinase						99.90%
SJFα		p38α, DC₅₀: 7.16 nM			p38δ, DC₅₀: 299 nM		99.61%
R1487 Hydrochloride		p38α, Kd: 0.2 nM	p38β, Kd: 29 nM				99.33%
PF-05381941		p38α, IC₅₀: 186 nM					99.73%
SR-318		p38α, IC₅₀: 5 nM	p38β, IC₅₀: 32 nM				99.89%
Anti-inflammatory agent 35	p38 MAPK						99.77%
RWJ-67657		p38α, IC₅₀: 1 μM	p38β, IC₅₀: 11 μM				99.75%
N-Feruloyloctopamine	p38 MAPK						99.91%
JNJ-49095397		p38α				p38γ	99.85%
p38 MAP Kinase Inhibitor III	p38 MAP kinase, IC₅₀: 0.9 μM						≥98.0%
SD-169		p38α MAPK, IC₅₀: 3.2 nM	p38β MAPK, IC₅₀: 122 nM				99.91%
p38α inhibitor 1		p38α					98.30%
p38α inhibitor 2		p38α MAPK, pIC₅₀: 9.6					98.03%
AL 8697		p38α, IC₅₀: 6 nM	p38β, IC₅₀: 82 nM				99.83%
AMG-548		p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM	≥99.0%
Emprumapimod hydrochloride		p38α					≥98.0%
SX 011		p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM		p38δ, IC₅₀: > 300,000 nM	p38γ, IC₅₀: > 300,000 nM	99.33%
p38 MAPK-IN-4	p38, IC₅₀: 35 nM
Ralimetinib		p38α MAPK, IC₅₀: 5.3 nM	p38β MAPK, IC₅₀: 3.2 nM
MW-150 hydrochloride		p38α, Ki: 101 nM
MW-150 dihydrochloride dihydrate		p38α, Ki: 101 nM
Talmapimod hydrochloride		p38α, IC₅₀: 9 nM	p38β, IC₅₀: 90 nM
p38-α MAPK-IN-4		p38α MAPK, IC₅₀: 1.5 μM
Halociline	p38 MAP kinase
p38 MAP Kinase Inhibitor IV		p38α, IC₅₀: 0.13 μM	p38β, IC₅₀: 0.55 μM		p38δ, IC₅₀: 8.63 μM
SJFδ		p38α, DC₅₀: 46.17 nM
p38-α MAPK-IN-5		p38α, IC₅₀: 0.1 nM	p38β, IC₅₀: 0.2 nM		p38δ, IC₅₀: 4100 nM	p38γ, IC₅₀: 944 nM
p38 MAPK-IN-3		p38α MAPK
SB-284851-BT		p38α, Kd: 0.47 nM
J-1149		p38α MAPK
MW108 hydrochloride		p38α MAPK, Ki: 114 nM
DCZ19931	p38 MAPK
Lucidone	p38 MAPK
AMG-548 hydrochloride		p38α, Ki: 0.5 nM dog p38α, Ki: 5.0 nM	p38β, Ki: 3.6 nM		p38δ, Ki: 2600 nM	p38γ, Ki: 4100 nM
CHMFL-ABL-053	p38, IC₅₀: 62 nM
Semapimod	p38 MAPK
NDs-IN-1	p38 MAPK
(aS)-PH-797804		p38α, IC₅₀: 26 nM	p38β, IC₅₀: 102 nM
JNK3 inhibitor-5		p38α, IC₅₀: 215.8 nM
Balanophonin	p38
SB 220025	p38, IC₅₀: 60 nM
Doramapimod (GMP)		p38α, IC₅₀: 38 nM	p38β, IC₅₀: 65 nM		p38δ, IC₅₀: 520 nM	p38γ, IC₅₀: 200 nM
PF-03715455		p38α, IC₅₀: 0.88 nM	p38β, IC₅₀: 23 nM
BMS-582949		p38α, IC₅₀: 13 nM
Cudraflavone B	p38 MAP kinase
p38α inhibitor 4		p38α, IC₅₀: 1.2 μM
Sugiol	p38 MAPK

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